Domain	Activity	Direct Medical Total: $8,035,178	Direct Nonmedical Total: $1,820,681	Indirect Total: $2,446,116	Total: $12,301,975
Medical response and outcomes for cases and contacts (nonuniversity-based care)	Acute medical care for cases	TOTAL: $453,805 Seven emergency room visits: $10,347^a Seven initial hospitalizations: $213,358 (facility)^b and $230,100 (nonfacility)^b Unavailable/inestimable costs: School health visits, urgent care visits, over-the-counter medications	Not applicable	TOTAL: $1,900 Patient productivity loss during hospitalization: $1,900^c Unavailable/inestimable costs: Lifetime productivity loss for living case, staff time diverted from regular activities, caregiver productivity loss	TOTAL: $455,705
	Close contact chemoprophylactic antibiotics	TOTAL: $932 Medications: $932^f	Not applicable	TOTAL: $2,100 Close contact productivity loss: $2,100^g	TOTAL: $3,032
	Mid-/long-term follow-up medical care	TOTAL: $165,051 Six cases, 12-month all-cause health care costs: $165,051^d Unavailable/inestimable costs: School health visits, over-the-counter medications, unbillable medical care	Not applicable	TOTAL: $6,816 Patient productivity loss due to lost wages during all-cause health care visits: $6,816^h Unavailable/inestimable costs: Staff time diverted from regular activities, caregiver productivity loss	TOTAL: $171,867
Public health response	University health center chemoprophylaxis and vaccination administration	TOTAL: $61,789 Chemoprophylactic antibiotics administered: $4,871ⁱ Chemoprophylactic antibiotics in stock: $13,310ⁱ Vaccine administered: $43,608ⁱ	TOTAL: $6,600 University staff time for increased administrative support: $6,600^j	TOTAL: $17,300 Patient productivity loss: $17,300^k	TOTAL: $85,689
	Public health awareness communication campaign and case investigation	TOTAL: $3,601 Serogrouping of isolates or clinical specimens (by slide agglutination or real-time PCR): $3,601^l	TOTAL: $225,027 Case investigation and incident command County staff time: $17,159^m State staff time: $148,541ⁿ Other state costs (e.g., transportation, shipping costs): $16,108ⁿ Nonuniversity health system: $2,936^o University health system: $21,743^p Staff time for close contact investigation: $18,540^q	Unavailable/inestimable costs: Staff time diverted from regular activities	TOTAL: $228,628
	Mass vaccination clinics	TOTAL: $7,350,000 Total vaccine cost for the 22,000 students at the University of Oregon is estimated at $7.1 million to $7.6 million at retail vaccination price^r Unavailable/inestimable costs: Vaccine administration fees	TOTAL: $51,097 Nonuniversity health system staff time: $14,396^p Portland State University Clinic exercise: $1,650^s Volunteer time during clinics: $16,380^t University staff time during clinics: $18,671^p Unavailable/inestimable costs: State, county, and university staff time for planning; nonvaccine physical resources	TOTAL: $150,000 Patient productivity loss: $150,000^u Unavailable/inestimable costs: Staff time diverted from regular activities	TOTAL: $7,551,097
	Long-term public health surveillance	Not applicable	TOTAL: $10,134 State public health staff: $4,055^v University staff: $6,079^v Unavailable/ inestimable costs: County staff time; nonincident command staff time	Unavailable/inestimable costs: Staff time diverted from regular activities	TOTAL: $10,134
Strategic communications	Media management	Not applicable	TOTAL: $14,312 Public health staff: $5,406ⁿ PR director nonuniversity health system: $801^p PR director nonuniversity health system: $8,105^p Unavailable/ inestimable costs: State, county, and university staff time for contact identification and interviews	Unavailable/inestimable costs: Staff time diverted from regular activities	TOTAL: $14,312
Strategic communications	Engagement with public officials or policymakers	Not applicable	TOTAL: $13,511 Public health staff: $5,406ⁿ PR director nonuniversity health system: $8,105^u	Unavailable/inestimable costs: Staff time diverted from regular activities	TOTAL: $13,511
Other		Not applicable	TOTAL: $1,500,000 Wrongful death lawsuit settlement: $1,500,000^w Unavailable/inestimable costs: Vaccine billing, legal consultation	Lifetime productivity loss due to death: $2,268,000^e Unavailable/inestimable costs: Effect on reputation of the school, resulting in actions to preserve/promote enrollment	TOTAL: $3,768,000